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Volume 9, Issue 0

2022pp 0—0

About the Cover

The cover for Oncoscience Volume 9, 2022 features Figure 2, "As expected, based on rapamycin-like p53-mediated gerosuppression, mTOR inhibition acts as a checkpoint in p53-mediated tumor suppression" from https://doi.org/10.18632/oncoscience.561
by Mikhail V. Blagosklonny

Research Papers

Systemic lipid peroxidation profile from patients with breast cancer changes according to the lymph nodal metastasis status

Stefania Tagliari de Oliveira, Monica Pavaneli Bessani, Thalita Basso Scandolara, Janaína Carla Silva, Aedra Carla Bufalo Kawassaki, Pâmella Aparecida Ferreira Fagotti, Vitor Teixeira Maito, Janoário Athanazio de Souza, Daniel Rech, Carolina Panis

https://doi.org/10.18632/oncoscience.550pp 1—10

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Editorials

β-Galactosylceramidase in cancer: more than a psychosine scavenger

Mirella Belleri, Marco Presta

https://doi.org/10.18632/oncoscience.551pp 11—12

Research Perspectives

Altos Labs and the quest for immortality: but can we live longer right now?

Mikhail V. Blagosklonny

https://doi.org/10.18632/oncoscience.552pp 13—16

Editorials

Towards the prevention of childhood leukemia

Kim E. Nichols, Isidro Sánchez-García

https://doi.org/10.18632/oncoscience.553pp 17—19

Research Perspectives

HSP90 as an emerging barrier to immune checkpoint blockade therapy

Daolin Tang, Rui Kang

https://doi.org/10.18632/oncoscience.554pp 20—22

Editorials

Epigenetics and cancer disparities: when nature might be nurture

I. King Jordan, Kara K. Lee, John F. McDonald, Leonardo Mariño-Ramírez

https://doi.org/10.18632/oncoscience.555pp 23—24

Crosstalk between KIF15 and AR in castrate-resistant prostate cancers

Hanny Yang, Xuesen Dong

https://doi.org/10.18632/oncoscience.556pp 25—26

Research Perspectives

A CRISPR-p53 interactome with potential implications for clinical CRISPR/Cas9 use

Long Jiang, Fredrik Wermeling

https://doi.org/10.18632/oncoscience.557pp 27—29

Potential roles of FAT1 somatic mutation in progression of head and neck cancer

Zhuo G. Chen, Yong Teng

https://doi.org/10.18632/oncoscience.558pp 30—32

Circulating tumor DNA as a therapy response marker in metastatic colorectal cancer

Xiaoju Max Ma, Stephanie J. Yaung

https://doi.org/10.18632/oncoscience.559pp 33—34

SLFN11’s surveillance role in protein homeostasis

Yasuhisa Murai, Ukhyun Jo, Yasuhiro Arakawa, Naoko Takebe, Yves Pommier

https://doi.org/10.18632/oncoscience.560pp 35—37

Commentary

As expected, based on rapamycin-like p53-mediated gerosuppression, mTOR inhibition acts as a checkpoint in p53-mediated tumor suppression

Mikhail V. Blagosklonny

https://doi.org/10.18632/oncoscience.561pp 38—41

Research Perspectives

Leveraging the scientific findings to develop therapeutic strategies for dormant breast cancer cells

Alejandra Ferrer, Yannick Kenfack, Andrew Petryna, Wadih Arap, Renata Pasqualini, Pranela Rameshwar

https://doi.org/10.18632/oncoscience.562pp 42—48

lncRNA HOTAIR functions and therapeutic perspectives

Sabrina Garbo, Marco Tripodi, Cecilia Battistelli

https://doi.org/10.18632/oncoscience.563pp 49—51

Editorials

MicroRNAs as predictive biomarkers of treatment response to tyrosine kinase inhibitors in hepatocellular carcinoma: how much is missing?

Laura Gramantieri, Francesca Fornari

https://doi.org/10.18632/oncoscience.564pp 52—54

Phenotypic heterogeneity and cooperation in the metastatic cascade

Katherine M. Young, Cynthia A. Reinhart-King

https://doi.org/10.18632/oncoscience.565pp 55—56

GM-CSF - an oncogenic driver of HER2+ breast leptomeningeal metastasis

Rachana Garg, Kai Jandial, Mike Chen

https://doi.org/10.18632/oncoscience.566pp 57—59

Research Perspectives

A murine model for human early/immature T-cell precursor acute lymphoblastic leukemia (EITP ALL)

Vijay Negi, Peter D. Aplan

https://doi.org/10.18632/oncoscience.567pp 60—63

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Editorials

Ikaros as a downstream mediator of BCR blockade therapy in B-cell non-Hodgkin lymphoma

Marcelo Lima Ribeiro, Emmanuel Normant, Gaël Roué

https://doi.org/10.18632/oncoscience.568pp 64—65

Research Perspectives

Modulation of heme and tumor vascular oxygenation- a novel strategy for lung cancer therapy

Poorva Ghosh, Ralph P. Mason, Li Liu, Li Zhang

https://doi.org/10.18632/oncoscience.569pp 66—69

Research Papers

Association between tumor mutations and meningioma recurrence in Grade I/II disease

Jonathan T. Dullea, Vikram Vasan, John W. Rutland, Corey M. Gill, Danielle Chaluts, Daniel Ranti, Ethan Ellis, Varun Subramanium, Annie Arrighi-Allisan, Yayoi Kinoshita, Russell B. McBride, Joshua Bederson, Michael Donovan, Robert Sebra, Melissa Umphlett, Raj K. Shrivastava

https://doi.org/10.18632/oncoscience.570pp 70—81

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Research Perspectives

Rapamycin in the context of Pascal’s Wager: generative pre-trained transformer perspective

ChatGPT Generative Pre-trained Transformer, Alex Zhavoronkov

https://doi.org/10.18632/oncoscience.571pp 82—84

PDF Full-TextPress Release