Figure 3 — Selective blood–brain barrier penetration and tumor targeting of nitrosylcobalamin in glioblastoma: Pharmacokinetics, tissue distribution, and synergistic activity with trail and temozolomide

Research Papers|Volume 13, Issue 0|pp. 120–129

Selective blood–brain barrier penetration and tumor targeting of nitrosylcobalamin in glioblastoma: Pharmacokinetics, tissue distribution, and synergistic activity with trail and temozolomide

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Figure 3.Serum nitrate and cobalamin levels following intraperitoneal administration of NO-Cbl in ratsSerum nitrate, cobalamin, and cerebral spinal fluid (CSF) cobalamin were measured in the same animals and at the same time points and treatment groups as in (Figure 2). Values are expressed as the mean ± standard deviation (n = 3 per group).