Figure 1.Nitrosylcobalamin (NO-Cbl) inhibits proliferation across NCI60 human tumor cell linesMean Inhibitory dose of 50% (ID50) +/− SEM values for NO-Cbl were determined for each major tumor type using the NCI60 cell line panel and sulforhodamine B assays. Renal, non-small cell lung cancer (NSCLC) and breast cancer cell lines were the most resistant, while leukemia cells were the most sensitive. Central nervous system tumor cell lines, highlighted in purple, exhibited intermediate sensitivity.
