Figure 3.Immunohistochemistry (IHC) and Immunofluorescence (IF) analysis of MD2 expression and immune cell infiltration in prostate cancer tissues(Upper panel) Representative IF images showing myeloid-derived suppressor cells (MDSCs; CD11b/CD33) and corresponding IHC staining for MD2 in patient tissues with varying prostate cancer (PCa) grades, metastatic lesions, and histologically normal adjacent tissue (NAT). (Lower panel) Representative IF images showing regulatory Tcell (Treg; CD25/Foxp3) infiltration and corresponding IHC staining for MD2 in PCa tissues with different tumor grades, metastasis, and NAT.
