Figure 2.Identification and concordance of SVs across multisite biopsies using WGS(A) Venn diagrams showing the overlap of SVs identified by five somatic SV callers at each sampling site. A substantial number of SVs were consistently detected by all five methods in HGSOC#1–#3, whereas HGSOC#4 showed a lower concordance, likely due to reduced sensitivity due to low tumor purity. (B) Venn diagrams showing the overlap of high-confidence SVs (see Methods) among different sampling sites within each case. Shared and unshared SVs reflect intratumor spatial heterogeneity.
